IER3 anticorps (AA 40-90)
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- Antigène Voir toutes IER3 Anticorps
- IER3 (Immediate Early Response 3 (IER3))
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Épitope
- AA 40-90
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IER3 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- IEX-1 Antibody is affinity chromatography purified via peptide column.
- Immunogène
- IEX1 antibody was raised against a 24 amino acid synthetic peptide near the center of human IEX1. The immunogen is located within amino acids 40 - 90 of IEX-1.
- Isotype
- IgG
- Top Product
- Discover our top product IER3 Anticorps primaire
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- Indications d'application
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IEX1 antibody can be used for detection of IEX1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- IEX-1 Antibody is supplied in PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,4 °C
- Stockage commentaire
- IEX-1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Antigène
- IER3 (Immediate Early Response 3 (IER3))
- Autre désignation
- IEX-1 (IER3 Produits)
- Synonymes
- anticorps DIF-2, anticorps DIF2, anticorps GLY96, anticorps IEX-1, anticorps IEX-1L, anticorps IEX1, anticorps PRG1, anticorps AI663993, anticorps cI-3, anticorps gly96, anticorps IER3, anticorps Dif2, anticorps Iex1, anticorps Ler3, anticorps Prg1, anticorps immediate early response 3, anticorps IER3, anticorps Ier3
- Sujet
- IEX-1 Antibody: IEX-1 is a stress inducible gene that is induced by ionizing radiation, ultraviolet radiation, and a variety of growth factors, i.e., FAS and TNF-α,. IEX-1 is widely expressed in epithelial and endocrine tissues, as well as in vascular endothelium. It plays an important role in the regulation of cellular growth, cell death and oncogenesis. IEX-1 is precisely regulated by multiple transcription factors such as p53, NF-κ,B/rel, Sp1 and c-Myc, to ensure rapid and transient expression of IEX-1 in cells under a variety of stress conditions. IEX-1 is expressed as both a longer form (IEX1L) and a splice variant, designated IEX1S. It is localized to the nucleus and perinuclear region. Overexpression of IEX-1 facilitates apoptosis and cell cycle progression, whereas disruption of IEX-1 expression is associated with decreases in both apoptosis and cell cycle progression.
- Poids moléculaire
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Predicted: 17 kDa
Observed: 17 kDa - ID gène
- 8870
- UniProt
- P46695
- Pathways
- Regulation of Carbohydrate Metabolic Process
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