NANOS2 anticorps (C-Term)

N° du produit ABIN6990923

Détail du produit anti-NANOS2 anticorps

Antigène: NANOS2 (Nanos Homolog 2 (NANOS2))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NANOS2 est non-conjugé

Application: ELISA, Western Blotting (WB)

Specificité: This Nanos2 antibody will not cross-react with either Nanos 1 or Nanos3.

Purification: Nanos2 Antibody is affinity chromatography purified via peptide column.

Immunogène: Nanos2 antibody was raised against a 13 amino acid synthetic peptide near the carboxy terminus of the human Nanos2. The immunogen is located within the last 50 amino acids of Nanos2.

Isotype: IgG

Information d'application

Indications d'application: Nanos2 antibody can be used for detection of Nanos2 by Western blot at 2 to 4 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Nanos2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: Nanos2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur NANOS2

Antigène: NANOS2 (Nanos Homolog 2 (NANOS2))

Autre désignation: Nanos2 (NANOS2 Produits)

Synonymes: anticorps NOS2, anticorps RGD1562436, anticorps nos2, anticorps nanos C2HC-type zinc finger 2, anticorps nanos homolog 2 (Drosophila), anticorps nanos 2, anticorps nanos2 protein, anticorps NANOS2, anticorps Nanos2, anticorps nanos2

Sujet: Nanos2 Antibody: Nanos is a zinc-finger containing, RNA-binding protein that has been implicated in germ cell development in both invertebrates and vertebrates. In drosophila, Nanos represses apoptosis during development to ensure proper germ-line development. Unlike Nanos1 whose expression in mice is dispensable, the Nanos2 and Nanos3 proteins are required for germ cell development. Nanos2-null primordial germ cells (PGCs) die only in the male gonads and show no defects in females, while Nanos3-null PGCs are lost during the migration stage regardless of sex. Nanos2 and Nanos3 have distinct expression patterns during embryo development, suggesting that these two proteins do not have redundant functions. However, expression of Nanos2 can at least partially replace Nanos3 function in a Nanos3-null background. Nanos3 expression can not rescue Nanos2-null defects.

ID gène: 339345

UniProt: P60321

Pathways: Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance