NANOS3 anticorps (C-Term)

N° du produit ABIN6990927

Détail du produit anti-NANOS3 anticorps

Antigène: NANOS3 (Nanos Homolog 3 (NANOS3))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NANOS3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificité: This Nanos3 antibody will not cross-react with either Nanos 1 or Nanos2.

Purification: Nanos3 Antibody is affinity chromatography purified via peptide column.

Immunogène: Nanos3 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of the human Nanos3. The immunogen is located within the last 50 amino acids of Nanos3.

Isotype: IgG

Information d'application

Indications d'application: Nanos3 antibody can be used for detection of Nanos3 by Western blot at 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Nanos3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: Nanos3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur NANOS3

Antigène: NANOS3 (Nanos Homolog 3 (NANOS3))

Autre désignation: Nanos3 (NANOS3 Produits)

Synonymes: anticorps NANOS1L, anticorps NOS3, anticorps nos3, anticorps cb725, anticorps nanos, anticorps nanos1, anticorps nos1, anticorps nanos C2HC-type zinc finger 3, anticorps nanos homolog 3 (Drosophila), anticorps nanos homolog 3, anticorps NANOS3, anticorps Nanos3, anticorps nanos3

Sujet: Nanos3 Antibody: Nanos is a zinc-finger containing, RNA-binding protein that has been implicated in germ cell development in both invertebrates and vertebrates. In Drosophila, Nanos represses apoptosis during development to ensure proper germ-line development. Unlike Nanos1 whose expression in mice is dispensable, the Nanos2 and Nanos3 proteins are required for germ cell development. Nanos2-null primordial germ cells (PGCs) die only in the male gonads and show no defects in females, while Nanos3-null PGCs are lost during the migration stage regardless of sex. Nanos2 and Nanos3 have distinct expression patterns during embryo development, suggesting that these two proteins do not have redundant functions. However, expression of Nanos2 can at least partially replace Nanos3 function in a Nanos3-null background. Nanos3 expression can not rescue Nanos2-null defects.

Poids moléculaire: Predicted: 19 kDa

Observed: 20 kDa

ID gène: 342977

UniProt: P60323

Pathways: ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Response to Molecule of Bacterial Origin, Myometrial Relaxation and Contraction, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling