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BICD1 anticorps (C-Term)

BICD1 Reactivité: Humain, Souris, Rat WB, ELISA, ICC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6990932
  • Antigène Voir toutes BICD1 Anticorps
    BICD1 (Bicaudal D Homolog 1 (BICD1))
    Épitope
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 14
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 13
    • 1
    Lapin
    Clonalité
    • 14
    Polyclonal
    Conjugué
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BICD1 est non-conjugé
    Application
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificité
    At least two isoforms of BICD1 are known to exist, this antibody will only recognize the larger isoform.
    Purification
    BICD1 Antibody is affinity chromatography purified via peptide column.
    Immunogène
    BICD1 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human BICD1. The immunogen is located within the last 50 amino acids of BICD1.
    Isotype
    IgG
    Top Product
    Discover our top product BICD1 Anticorps primaire
  • Indications d'application
    BICD1 antibody can be used for detection of BICD1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    BICD1 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,4 °C
    Stockage commentaire
    BICD1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène
    BICD1 (Bicaudal D Homolog 1 (BICD1))
    Autre désignation
    BICD1 (BICD1 Produits)
    Synonymes
    anticorps BICD, anticorps B830009D06Rik, anticorps mKIAA4125, anticorps bicaudal D homolog 1 L homeolog, anticorps BICD cargo adaptor 1, anticorps bicaudal D homolog 1 (Drosophila), anticorps bicd1.L, anticorps BICD1, anticorps Bicd1
    Sujet
    BICD1 Antibody: BICD1 was initially identified as the human homolog to Drosophila Bicaudal-D protein that forms part of the cytoskeleton and mediates the correct sorting of mRNAs for oocyte- and axis-determining factors during oogenesis. BICD1 can bind to dynein-dynactin and co-localizes with Rab6A on the trans-Golgi network and cytoplasmic vesicles, suggesting BICD1 regulates COPI-independent Golgi-ER transport. BICD1 will also interact with Rab6B, a Rab6 isoform that is expressed primarily in brain. Live cell imaging showed bi-directional movement of Rab6B structures in SK-N-SH neurites, indicating that BICD1 is involved in the Rab6B regulation of retrograde cargo transport in neuronal cells.
    ID gène
    636
    NCBI Accession
    NP_001705
    UniProt
    Q96G01
    Pathways
    Ribonucleoprotein Complex Subunit Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, Maintenance of Protein Location
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