IL-34 anticorps (N-Term)

N° du produit ABIN6990969

Cet anticorps anti-IL-34 Polyclonal Lapin (ABIN6990969) détecte spécifiquement IL-34 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour IL-34 anticorps (N-Term) (ABIN6990969)

Antigène: IL-34 (IL34) (Interleukin 34 (IL34))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-34 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-IL-34 anticorps

Épitope: AA 30-80, N-Term

Purification: IL-34 Antibody is affinity chromatography purified via peptide column.

Immunogène: IL-34 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human IL-34. The immunogen is located within amino acids 30 - 80 of IL-34.

Isotype: IgG

Information d'application

Indications d'application: IL-34 antibody can be used for the detection of IL-34 by Western blot at 0.25 μ,g/mL. Despite its predicted molecular weight, IL-34 will often run at higher molecular weight in SDS-PAGE.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: IL-34 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: IL-34 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur IL-34

Antigène: IL-34 (IL34) (Interleukin 34 (IL34))

Autre désignation: IL-34

Sujet: IL-34 Antibody: Interleukin-34 (IL-34) was identified through a functional screening of a library of secreted proteins after transfection of an embryonic kidney cell line with recombinant cDNAs. Flow cytometry and monocyte viability assays demonstrated increased survival and/or proliferation of monocytes induced by IL-34 and specific binding of IL-34 to CD14+ monocytes. IL-34 is a second ligand to the colony stimulating factor (CSF)-1 receptor in addition to CSF1. Like CSF1, IL-34 stimulates phosphorylation of ERK1 and ERK2 in human monocytes and induces differentiation of bone marrow cells into macrophages.

Poids moléculaire: Predicted: 26 kDa

Observed: 42-48 kDa

ID gène: 146433

UniProt: Q6ZMJ4

Pathways: Signalisation RTK