FNIP2 anticorps (C-Term)

N° du produit ABIN6991067

L’anticorps anti-FNIP2 Polyclonal Lapin est utilisé pour la détection de FNIP2 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA et IHC (p).

Aperçu rapide pour FNIP2 anticorps (C-Term) (ABIN6991067)

Antigène: FNIP2 (Folliculin Interacting Protein 2 (FNIP2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FNIP2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-FNIP2 anticorps

Épitope: AA 860-910, C-Term

Specificité: Multiple isoforms of FNIP2 are known to exist. This antibody is predicted to not cross-react with FNIP1.

Purification: FNIP2 Antibody is affinity chromatography purified via peptide column.

Immunogène: FNIP2 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human FNIP2. The immunogen is located within amino acids 860 - 910 of FNIP2.

Isotype: IgG

Information d'application

Indications d'application: FNIP2 antibody can be used for detection of FNIP2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in rat samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: FNIP2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: FNIP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur FNIP2

Antigène: FNIP2 (Folliculin Interacting Protein 2 (FNIP2))

Autre désignation: FNIP2

Sujet: FNIP2 Antibody: FNIP2 is the second protein found to interact with folliculin, the product of the Birt-Hogg-Dube (BHD) gene. Folliculin is thought to act as a tumor suppressor as mutations or loss of heterozygosity in this gene are associated with BHD syndrome-related renal tumors. Folliculin and FNIP1, a protein that shares 49 % identity to FNIP2, bind to AMPK, an important energy sensor in cells that negatively regulates the mammalian target of rapamycin (mTOR), a protein that is thought to be the master switch for cell growth and proliferation. FNIP1 and FNIP2 are able to form homo- and heteromeric multimers, suggesting these proteins may have a functional relationship.

ID gène: 57600

NCBI Accession: NP_065891

UniProt: Q9P278