alpha Tubulin anticorps (N-Term)

N° du produit ABIN6991087

Cet anticorps Poulet Polyclonal détecte spécifiquement alpha Tubulin dans WB et ELISA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour alpha Tubulin anticorps (N-Term) (ABIN6991087)

Antigène: alpha Tubulin (TUBA1)

Reactivité: Humain, Souris, Rat

Hôte: Poulet

Clonalité: Polyclonal

Conjugué: Cet anticorp alpha Tubulin est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-alpha Tubulin anticorps

Épitope: AA 140-190, N-Term

Purification: Alpha-tubulin Antibody is affinity chromatography purified via peptide column.

Immunogène: Tubulin antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human Tubulin. The immunogen is located within amino acids 140 - 190 of Alpha-tubulin.

Isotype: IgY

Information d'application

Indications d'application: Tubulin antibody can be used for detection of Tubulin by Western blot at 0.5 - 1 μ,g/mL.

Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Alpha-tubulin Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: Alpha-tubulin antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur alpha Tubulin

Antigène: alpha Tubulin (TUBA1)

Autre désignation: Alpha-tubulin

Sujet: Alpha-tubulin Antibody: Alpha-tubulin belongs to the tubulin superfamily, which is composed of six distinct families. Along with beta-tubulins, alpha-tubulins are the major components of microtubules. These microtubules are involved in a wide variety of cellular activities ranging from mitosis and transport events to cell movement and the maintenance of cell shape. Alpha- and beta-tubulin dimers are assembled to 13 protofilaments that form a microtubule of 22-nm diameter. Tyrosine ligase adds a C-terminal tyrosine to monomeric alpha-tubulin. Assembled microtubules can again be detyrosinated by a cytoskeleton-associated carboxypeptidase. Another post-translational modification of detyrosinated alpha-tubulin is C-terminal polyglutamylation, which is characteristic of microtubules in neuronal cells and the mitotic spindle. Like GAPDH and beta-Actin, this antibody makes an excellent loading control in immunoblots.

ID gène: 7278

NCBI Accession: NP_005992

UniProt: Q13748

Pathways: Dynamique des Microtubules