RGS21 anticorps (AA 40-90)

N° du produit ABIN6991130

L’anticorps anti-RGS21 Polyclonal Lapin est utilisé pour la détection de RGS21 dans des échantillons de Humain. Il a été validé pour WB, ELISA, IHC (p) et IF.

Aperçu rapide pour RGS21 anticorps (AA 40-90) (ABIN6991130)

Antigène: RGS21 (Regulator of G-Protein Signaling 21 (RGS21))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RGS21 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-RGS21 anticorps

Épitope: AA 40-90

Purification: RGS21 Antibody is affinity chromatography purified via peptide column.

Immunogène: RGS21 antibody was raised against a 16 amino acid synthetic peptide near the center of human RGS21. The immunogen is located within amino acids 40 - 90 of RGS21.

Isotype: IgG

Information d'application

Indications d'application: RGS21 antibody can be used for detection of RGS21 by Western blot at 0.5 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: RGS21 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: RGS21 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur RGS21

Antigène: RGS21 (Regulator of G-Protein Signaling 21 (RGS21))

Autre désignation: RGS21

Sujet: RGS21 Antibody: Regulator of G-protein signaling (RGS) proteins contain an 120 amino acid conserved domain, termed the RGS domain, that acts as a GTPase-activating protein that acts to reduce the signal transmitted by the receptor-activated G-alpha subunit. RGS21 is a recently identified member of this family that has been reported to be selectively expressed in subpopulations of taste bud cells and co-expressed with bitter and sweet transduction components such as alpha-gusticin, phospholipase Cbeta2, T1R2/T1R3 sweet taste receptors and T2R bitter taste receptors. Other reports indicate that RGS21 is more widely expressed. Binding assays demonstrate that RGS21 binds alpha-gusticin in a conformation-dependent manner and may do the same with T1R receptors, suggesting that RGS21 may play a role in sweet and bitter taste transduction processes.

ID gène: 431704

NCBI Accession: NP_001034241

UniProt: Q2M5E4

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling