HAAO anticorps (N-Term)
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- Antigène Voir toutes HAAO Anticorps
- HAAO (3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))
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Épitope
- AA 30-80, N-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HAAO est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Purification
- HAAO Antibody is affinity chromatography purified via peptide column.
- Immunogène
- HAAO antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human HAAO. The immunogen is located within amino acids 30 - 80 of HAAO.
- Isotype
- IgG
- Top Product
- Discover our top product HAAO Anticorps primaire
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- Indications d'application
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HAAO antibody can be used for detection of HAAO by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- HAAO Antibody is supplied in PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,4 °C
- Stockage commentaire
- HAAO antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Antigène
- HAAO (3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))
- Autre désignation
- HAAO (HAAO Produits)
- Synonymes
- anticorps Afu2g17450, anticorps 0610007K21Rik, anticorps 0610012J07Rik, anticorps 3-HAO, anticorps 3-HAOxase, anticorps 3HAO, anticorps zgc:103585, anticorps HAO, anticorps 3-hydroxyanthranilate 3,4-dioxygenase, anticorps 3-hydroxyanthranilate 3,4-dioxygenase L homeolog, anticorps SPO1774, anticorps CNB05620, anticorps AFUA_2G17450, anticorps Bcep18194_C7641, anticorps Kfla_5491, anticorps Micau_4935, anticorps RBRH_03005, anticorps Krodi_1278, anticorps haao, anticorps HAAO, anticorps Haao, anticorps haao.L
- Sujet
- HAAO Antibody: HAAO (3-Hydroxyanthranilate 3, 4-dioxygenase) is a monomeric cytosolic protein of the family of intramolecular dioxygenases containing non-heme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is present in low amounts in the central nervous system. This enzyme participates in tryptophan metabolism. It employs one cofactor, iron. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurological and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN. Furthermore, recent study shows that HAAO are excellent candidate biomarkers for detecting ovarian cancer.
- ID gène
- 23498
- NCBI Accession
- NP_036337
- UniProt
- P46952
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