RUSC2 anticorps (C-Term)

N° du produit ABIN6991196

L’anticorps anti-RUSC2 Polyclonal Lapin est utilisé pour la détection de RUSC2 dans des échantillons de Humain. Il a été validé pour ELISA et IHC (p).

Aperçu rapide pour RUSC2 anticorps (C-Term) (ABIN6991196)

Antigène: RUSC2 (RUN and SH3 Domain Containing 2 (RUSC2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RUSC2 est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-RUSC2 anticorps

Épitope: AA 1410-1460, C-Term

Specificité: At least three isoforms are known to exist, this antibody will only detect the longest isoform. This antibody is predicted to not cross-react with RUSC1.

Purification: RUSC2 Antibody is affinity chromatography purified via peptide column.

Immunogène: RUSC2 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human RUSC2. The immunogen is located within amino acids 1410 - 1460 of RUSC2.

Isotype: IgG

Information d'application

Indications d'application: RUSC2 antibody can be used for detection of RUSC2 by immunohistrochemistry at 5 μ,g/mL.

Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: RUSC2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: RUSC2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur RUSC2

Antigène: RUSC2 (RUN and SH3 Domain Containing 2 (RUSC2))

Autre désignation: RUSC2

Sujet: RUSC2 Antibody: RUSC2, also known as Iporin, shares with the related protein RUSC1 a common domain structure of RUN, leucine zipper and SH3 domain in addition to over 30 % amino acid identity. RUSC2 is a rab1-interacting protein that also interacts with GM130, another rab1-interacting protein. RUSC2 interacts with specific rab1 isoforms with different rab-binding specificity. It has been suggested that RUSC2 may function as a link between the targeting of ER derived vesicles triggered by the rab1 GTPase and a signaling pathway composed of proteins containing SH3 and/or poly-proline regions.

ID gène: 9853

NCBI Accession: NP_001098673

UniProt: Q8N2Y8