RUSC2 anticorps (N-Term)
Aperçu rapide pour RUSC2 anticorps (N-Term) (ABIN6991637)
Antigène
Voir toutes RUSC2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 70-120, N-Term
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Specificité
- At least three isoforms are known to exist, this antibody will detect all three isoforms. This antibody is predicted to not cross-react with RUSC1.
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Purification
- RUSC2 Antibody is affinity chromatography purified via peptide column.
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Immunogène
- RUSC2 antibody was raised against an 18 amino acid synthetic peptide from near the amino terminus of human RUSC2. The immunogen is located within amino acids 70 - 120 of RUSC2.
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Isotype
- IgG
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Indications d'application
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RUSC2 antibody can be used for detection of RUSC2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- RUSC2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,4 °C
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Stockage commentaire
- RUSC2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- RUSC2 (RUN and SH3 Domain Containing 2 (RUSC2))
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Autre désignation
- RUSC2
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Sujet
- RUSC2 Antibody: RUSC2, also known as Iporin, shares with the related protein RUSC1 a common domain structure of RUN, leucine zipper and SH3 domain in addition to over 30 % amino acid identity. RUSC2 is a rab1-interacting protein that also interacts with GM130, another rab1-interacting protein. RUSC2 interacts with specific rab1 isoforms with different rab-binding specificity. It has been suggested that RUSC2 may function as a link between the targeting of ER derived vesicles triggered by the rab1 GTPase and a signaling pathway composed of proteins containing SH3 and/or poly-proline regions.
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ID gène
- 9853
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NCBI Accession
- NP_055621
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UniProt
- Q8N2Y8
Antigène
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