CENPO anticorps (AA 170-220)

N° du produit ABIN6991201

Cet anticorps Lapin Polyclonal détecte spécifiquement CENPO dans ELISA et WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour CENPO anticorps (AA 170-220) (ABIN6991201)

Antigène: CENPO (Centromere Protein O (CENPO))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CENPO est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-CENPO anticorps

Épitope: AA 170-220

Purification: CENPO Antibody is affinity chromatography purified via peptide column.

Immunogène: CENPO antibody was raised against a 16 amino acid synthetic peptide from near the center of human CENPO. The immunogen is located within amino acids 170 - 220 of CENPO.

Isotype: IgG

Information d'application

Indications d'application: CENPO antibody can be used for detection of CENPO by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: CENPO Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: CENPO antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur CENPO

Antigène: CENPO (Centromere Protein O (CENPO))

Autre désignation: CENPO

Sujet: CENPO Antibody: Accurate chromosome segregation during mitosis requires a kinetochore to assemble correctly at the centromere of each chromatid and form a dynamic interface with the microtubules of the mitotic spindle. The kinetochore assembly includes the multisubunit CENP-H/I complex which can be divided into three functional classes based on phenotype analysis. One of these classes is referred to as the CENP-O class of proteins of which CENPO is the exemplar. These proteins form a stable complex with each other and are required for proper kinetochore function and for recovery from mitotic spindle damage. CENPO has also been shown to be an auto-antigen in a small population of anti-centromere antibodies- (ACA-) positive patients with sclerodoma.

ID gène: 79172

NCBI Accession: NP_077298

UniProt: Q9BU64