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SIPA1L3 anticorps (N-Term)

L’anticorps Lapin Polyclonal anti-SIPA1L3 a été validé pour WB, ELISA, IHC (p) et IF. Il convient pour détecter SIPA1L3 dans des échantillons de Humain, Souris et Rat.
N° du produit ABIN6991229

Aperçu rapide pour SIPA1L3 anticorps (N-Term) (ABIN6991229)

Antigène

SIPA1L3 (Signal-Induced Proliferation-Associated 1 Like 3 (SIPA1L3))

Reactivité

  • 5
  • 2
  • 1
  • 1
Humain, Souris, Rat

Hôte

  • 5
Lapin

Clonalité

  • 5
Polyclonal

Conjugué

  • 5
Cet anticorp SIPA1L3 est non-conjugé

Application

Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • Épitope

    • 2
    • 1
    • 1
    • 1
    AA 80-130, N-Term

    Purification

    SIPA1L3 Antibody is affinity chromatography purified via peptide column.

    Immunogène

    SIPA1L3 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human SIPA1L3. The immunogen is located within amino acids 80 - 130 of SIPA1L3.

    Isotype

    IgG
  • Indications d'application

    SIPA1L3 antibody can be used for detection of SIPA1L3 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    SIPA1L3 Antibody is supplied in PBS containing 0.02 % sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C,4 °C

    Stockage commentaire

    SIPA1L3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène

    SIPA1L3 (Signal-Induced Proliferation-Associated 1 Like 3 (SIPA1L3))

    Autre désignation

    SIPA1L3

    Sujet

    SIPA1L3 Antibody: Signal-induced proliferation associated-like protein 2 (SIPA1L3) is a member of the SIPA1 family of RapGAPs. SIPA1L3 was cloned as a novel molecular component of tight junctions and adherens junctions, suggesting that may function to balance Rap1 by counteracting RapGEFs. Recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is possible that SIPA1L3 plays other roles development and cell proliferation.

    ID gène

    23094

    NCBI Accession

    NP_055888

    UniProt

    O60292
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