TMEM38A anticorps (C-Term)

N° du produit ABIN6991239

Cet anticorps anti-TMEM38A est un anticorps Lapin Polyclonal détectant TMEM38A dans WB, ELISA et IF. Adapté pour Humain, Rat et Souris.

Aperçu rapide pour TMEM38A anticorps (C-Term) (ABIN6991239)

Antigène: TMEM38A (Transmembrane Protein 38A (TMEM38A))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMEM38A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-TMEM38A anticorps

Épitope: C-Term

Purification: TMEM38A Antibody is affinity chromatography purified via peptide column.

Immunogène: TMEM38A antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human TMEM38A. The immunogen is located within the last 50 amino acids of TMEM38A.

Isotype: IgG

Information d'application

Indications d'application: TMEM38A antibody can be used for detection of TMEM38A by Western blot at 1 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: TMEM38A Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: TMEM38A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur TMEM38A

Antigène: TMEM38A (Transmembrane Protein 38A (TMEM38A))

Autre désignation: TMEM38A

Sujet: TMEM38A Antibody: TMEM38A and TMEM38B are two recently identified trimeric intracellular cation (TRIC) channel subtypes. TMEM38A is preferentially expressed in excitable tissues such as striated muscle and brain and localizes to the sarcoplasmic reticulum (SR) in muscle tissues. Mice deficient in both TMEM38A and TMEM38B suffer embryonic cardiac failure, the cardiac myocytes display severe dysfunction in SR Ca2+ handling, weakened Ca2+ release, and reduced K+ permeability indicating that the TRIC cation channels are likely to act as counter-ion channels that function in synchronization with Ca2+ release from intracellular stores. Other experiments have shown that TMEM38A and TMEM38B can act with junctophilin proteins to support efficient ryanodine receptor-mediated Ca2+ release in muscle cells.

ID gène: 79041

UniProt: Q9H6F2