TMEM38A anticorps (C-Term)

N° du produit ABIN500984

Détail du produit anti-TMEM38A anticorps

Antigène: TMEM38A (Transmembrane Protein 38A (TMEM38A))

Épitope: C-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMEM38A est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects TMEM38A.

Purification: Peptide affinity chromatography

Immunogène: TMEM38A antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human TMEM38A.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur TMEM38A

Antigène: TMEM38A (Transmembrane Protein 38A (TMEM38A))

Autre désignation: TMEM38A (TMEM38A Produits)

Synonymes: anticorps zgc:77831, anticorps MGC75707, anticorps TMEM38A, anticorps TRIC-A, anticorps TRICA, anticorps 1110001E17Rik, anticorps AI413399, anticorps mg33a, anticorps RGD1307901, anticorps Srp-27, anticorps transmembrane protein 38A, anticorps transmembrane protein 38a, anticorps transmembrane protein 38A L homeolog, anticorps tmem38a, anticorps CpipJ_CPIJ011791, anticorps CpipJ_CPIJ013655, anticorps TMEM38A, anticorps Tmem38a, anticorps tmem38a.L

Sujet: TMEM38A and TMEM38B are two recently identified trimeric intracellular cation (TRIC) channel subtypes. TMEM38A is preferentially expressed in excitable tissues such as striated muscle and brain and localizes to the sarcoplasmic reticulum (SR) in muscle tissues. Mice deficient in both TMEM38A and TMEM38B suffer embryonic cardiac failure, the cardiac myocytes display severe dysfunction in SR Ca2+ handling, weakened Ca2+ release, and reduced K+ permeability indicating that the TRIC cation channels are likely to act as counter-ion channels that function in synchronization with Ca2+ release from intracellular stores. Other experiments have shown that TMEM38A and TMEM38B can act with junctophilin proteins to support efficient ryanodine receptor-mediated Ca2+ release in muscle cells.Synonyms: TRIC-A, TRICA, Transmembrane protein 38A, Trimeric intracellular cation channel type A

ID gène: 79041