SIRT3 anticorps (AA 180-230)

N° du produit ABIN6991344

Cet anticorps anti-SIRT3 est un anticorps Poulet Polyclonal détectant SIRT3 dans WB et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour SIRT3 anticorps (AA 180-230) (ABIN6991344)

Antigène: SIRT3 (Sirtuin 3 (SIRT3))

Reactivité: Humain, Souris, Rat

Hôte: Poulet

Clonalité: Polyclonal

Conjugué: Cet anticorp SIRT3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-SIRT3 anticorps

Épitope: AA 180-230

Purification: SIRT3 Antibody is affinity chromatography purified via peptide column.

Immunogène: SIRT3 antibody was raised against a 17 amino acid synthetic peptide near the center of human SIRT3. The immunogen is located within amino acids 180 - 230 of SIRT3.

Isotype: IgY

Information d'application

Indications d'application: SIRT3 antibody can be used for detection of SIRT3 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SIRT3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SIRT3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur SIRT3

Antigène: SIRT3 (Sirtuin 3 (SIRT3))

Autre désignation: SIRT3

Sujet: SIRT3 Antibody: The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence, lifespan extension and several age-related diseases. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) and SIRT3 is the only sirtuin whose increased expression has been shown to correlate with an extended life span in humans. It is localized in the mitochondrial matrix, where it regulates the acetylation levels of metabolic enzymes, including acetyl coenzyme A synthetase 2. SIRT3 is stress-responsive and its increased expression protects myocytes from genotoxic and oxidative stress-mediated cell death.

ID gène: 23410

NCBI Accession: NP_036371

UniProt: Q9NTG7