NLRP10 anticorps (N-Term)

N° du produit ABIN6991406

Détail du produit anti-NLRP10 anticorps

Antigène: NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP10 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purification: NALP10 Antibody is affinity chromatography purified via peptide column.

Immunogène: NALP10 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human NALP10. The immunogen is located within the first 50 amino acids of NALP10.

Isotype: IgG

Information d'application

Indications d'application: NALP10 antibody can be used for detection of NALP10 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: NALP10 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: NALP10 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur NLRP10

Antigène: NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))

Autre désignation: NALP10 (NLRP10 Produits)

Synonymes: anticorps CLR11.1, anticorps NALP10, anticorps NOD8, anticorps PAN5, anticorps PYNOD, anticorps 6430548I20Rik, anticorps Nalp10, anticorps Napl10, anticorps Pynod, anticorps NLR family pyrin domain containing 10, anticorps NLR family, pyrin domain containing 10, anticorps NLRP10, anticorps Nlrp10

Sujet: NALP10 Antibody: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP10 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It was initially identified as PYNOD, an Apaf-1-like protein that binds to ASC, caspase-1 and IL-1β, inhibiting the autoprocessing of caspase-1, caspase-1-mediated IL-1β, processing, and ASC aggregation. NALP10 is thus a potent regulator of apoptosis and inflammation.

ID gène: 338322

NCBI Accession: NP_789791

UniProt: Q86W26

Pathways: Inflammasome