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PRR5 anticorps (C-Term)

L’anticorps Lapin Polyclonal anti-PRR5 a été validé pour WB, ELISA, IF et IHC (p). Il convient pour détecter PRR5 dans des échantillons de Humain, Souris et Rat.
N° du produit ABIN6991523

Aperçu rapide pour PRR5 anticorps (C-Term) (ABIN6991523)

Antigène

Voir toutes PRR5 Anticorps
PRR5 (Proline Rich 5 (Renal) (PRR5))

Reactivité

  • 34
  • 12
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Humain, Souris, Rat

Hôte

  • 42
Lapin

Clonalité

  • 42
Polyclonal

Conjugué

  • 17
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp PRR5 est non-conjugé

Application

  • 34
  • 13
  • 13
  • 11
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Épitope

    • 15
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 310-360, C-Term

    Specificité

    PRR5 antibody is predicted to not cross-react with other Protor protein family members.

    Purification

    PRR5 Antibody is affinity chromatography purified via peptide column.

    Immunogène

    PRR5 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human PRR5. The immunogen is located within amino acids 310 - 360 of PRR5.

    Isotype

    IgG
  • Indications d'application

    PRR5 antibody can be used for detection of PRR5 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    PRR5 Antibody is supplied in PBS containing 0.02 % sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C,4 °C

    Stockage commentaire

    PRR5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène

    PRR5 (Proline Rich 5 (Renal) (PRR5))

    Autre désignation

    PRR5

    Sujet

    PRR5 Antibody: Proline-rich protein 5 (PRR5), also known as Protor-1, is a 388 amino acid protein in Protor family, is thought to act as a tumor suppressor in breast and colorectal tumorigenesis. PRR5 is widely expressed and possesses two RICTOR interaction sites and a C-terminal Proline rich region. It promotes Rapamycin complex 2 (mTORC2) activity. There are four isoforms of PRR5 that are produced as a result of alternative splicing events and these isoforms play an important role in the modulation of platelet-derived growth factor signaling and in the regulation of PDGFR-beta expression.

    ID gène

    55615

    NCBI Accession

    NP_851850

    UniProt

    P85299

    Pathways

    Signalisation PI3K-Akt
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