PRR5 anticorps (C-Term)

N° du produit ABIN6991523

Détail du produit anti-PRR5 anticorps

Antigène: PRR5 (Proline Rich 5 (Renal) (PRR5))

Épitope: AA 310-360, C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRR5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: PRR5 antibody is predicted to not cross-react with other Protor protein family members.

Purification: PRR5 Antibody is affinity chromatography purified via peptide column.

Immunogène: PRR5 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human PRR5. The immunogen is located within amino acids 310 - 360 of PRR5.

Isotype: IgG

Information d'application

Indications d'application: PRR5 antibody can be used for detection of PRR5 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PRR5 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: PRR5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur PRR5

Antigène: PRR5 (Proline Rich 5 (Renal) (PRR5))

Autre désignation: PRR5 (PRR5 Produits)

Synonymes: anticorps AU043908, anticorps Arhgap8, anticorps C030017C09Rik, anticorps C78947, anticorps Protor-1, anticorps Protor1, anticorps FLJ20185k, anticorps PP610, anticorps PROTOR-1, anticorps PROTOR1, anticorps pp610, anticorps protor1, anticorps protor2, anticorps proline rich 5 (renal), anticorps proline rich 5, anticorps proline rich 5 L homeolog, anticorps Prr5, anticorps PRR5, anticorps prr5.L

Sujet: PRR5 Antibody: Proline-rich protein 5 (PRR5), also known as Protor-1, is a 388 amino acid protein in Protor family, is thought to act as a tumor suppressor in breast and colorectal tumorigenesis. PRR5 is widely expressed and possesses two RICTOR interaction sites and a C-terminal Proline rich region. It promotes Rapamycin complex 2 (mTORC2) activity. There are four isoforms of PRR5 that are produced as a result of alternative splicing events and these isoforms play an important role in the modulation of platelet-derived growth factor signaling and in the regulation of PDGFR-beta expression.

ID gène: 55615

NCBI Accession: NP_851850

UniProt: P85299

Pathways: Signalisation PI3K-Akt