Translin anticorps (C-Term)

N° du produit ABIN6991538

L’anticorps Lapin Polyclonal anti-Translin a été validé pour WB, ELISA, IF et IHC (p). Il convient pour détecter Translin dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Translin anticorps (C-Term) (ABIN6991538)

Antigène: Translin (TSN)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Translin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Translin anticorps

Épitope: C-Term

Specificité: At least two isoforms of Translin are known to exist, this antibody will detect both.

Purification: Translin Antibody is affinity chromatography purified via peptide column.

Immunogène: Translin antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human Translin. The immunogen is located within the last 50 amino acids of Translin.

Isotype: IgG

Information d'application

Indications d'application: Translin antibody can be used for detection of Translin by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Translin Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Translin antibody can be stored at 4 °C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur Translin

Antigène: Translin (TSN)

Autre désignation: Translin

Sujet: Translin Antibody: Translin is a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. Recent evidence suggests that in combination with a binding partner Trax, Translin binds RNA and mediates trafficking in neurons.

ID gène: 7247

NCBI Accession: NP_004613

UniProt: Q15631