TMEM88 anticorps (C-Term)

N° du produit ABIN6991552

Détail du produit anti-TMEM88 anticorps

Antigène: TMEM88 (Transmembrane Protein 88 (TMEM88))

Épitope: AA 110-160, C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMEM88 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: At least two isoforms of TMEM88 are known to exist, this antibody will recognize both isoforms.

Purification: TMEM88 Antibody is affinity chromatography purified via peptide column.

Immunogène: TMEM88 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human TMEM88. The immunogen is located within amino acids 110 - 160 of TMEM88.

Isotype: IgG

Information d'application

Indications d'application: TMEM88 antibody can be used for detection of TMEM88 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: TMEM88 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: TMEM88 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur TMEM88

Antigène: TMEM88 (Transmembrane Protein 88 (TMEM88))

Autre désignation: TMEM88 (TMEM88 Produits)

Synonymes: anticorps 2600017H02Rik, anticorps RGD1561781, anticorps zgc:77242, anticorps transmembrane protein 88, anticorps transmembrane protein 88B, anticorps transmembrane protein 88 a, anticorps Tmem88, anticorps TMEM88, anticorps TMEM88B, anticorps tmem88, anticorps tmem88a

Sujet: TMEM88 Antibody: Transmembrane protein 88 (TMEM88) is a two-transmembrane-type protein whose C-terminal tail has been shown to bind the PDZ domain of Dishevelled (Dvl), one of the key components in Wnt signaling pathways. TMEM88 attentuated the Wnt/beta-catenin signaling induced by Wnt-1 ligand in a dose-dependent manner and knockdown of TMEM88 by RNAi increased Wnt activity, suggesting that TMEM88 plays a role in regulating Wnt signaling in a context-dependent manner.

ID gène: 92162

UniProt: Q6PEY1