TMEM88 anticorps (C-Term)

N° du produit ABIN783510

Détail du produit anti-TMEM88 anticorps

Antigène: TMEM88 (Transmembrane Protein 88 (TMEM88))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMEM88 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects TMEM88 / TMEM88A at C-term.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogène: 19 amino acid peptide near the carboxy terminus of human TMEM88

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Détails sur TMEM88

Antigène: TMEM88 (Transmembrane Protein 88 (TMEM88))

Abstract: TMEM88 Produits

Synonymes: anticorps 2600017H02Rik, anticorps RGD1561781, anticorps zgc:77242, anticorps transmembrane protein 88, anticorps transmembrane protein 88B, anticorps transmembrane protein 88 a, anticorps Tmem88, anticorps TMEM88, anticorps TMEM88B, anticorps tmem88, anticorps tmem88a

Sujet: Transmembrane protein 88 (TMEM88) is a two-transmembrane-type protein whose C-terminal tail has been shown to bind the PDZ domain of Dishevelled (Dvl), one of the key components in Wnt signaling pathways. TMEM88 attentuated the Wnt/beta-catenin signaling induced by Wnt-1 ligand in a dose-dependent manner and knockdown of TMEM88 by RNAi increased Wnt activity, suggesting that TMEM88 plays a role in regulating Wnt signaling in a context-dependent manner.Synonyms: Transmembrane protein 88

ID gène: 92162

NCBI Accession: NP_981956

UniProt: Q6PEY1