SEC62 anticorps (C-Term)

N° du produit ABIN6991578

Cet anticorps anti-SEC62 est un anticorps Lapin Polyclonal détectant SEC62 dans WB, ELISA, IHC (p) et IF. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour SEC62 anticorps (C-Term) (ABIN6991578)

Antigène: SEC62 (TLOC1) (Translocation Protein 1 (TLOC1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SEC62 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-SEC62 anticorps

Épitope: AA 270-320, C-Term

Specificité: SEC62 antibody is predicted to not cross-react with other SEC proteins. Multiple isoforms of SEC62 are known to exist.

Purification: SEC62 Antibody is affinity chromatography purified via peptide column.

Immunogène: SEC62 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human SEC62. The immunogen is located within amino acids 270 - 320 of SEC62.

Isotype: IgG

Information d'application

Indications d'application: SEC62 antibody can be used for detection of SEC62 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SEC62 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SEC62 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur SEC62

Antigène: SEC62 (TLOC1) (Translocation Protein 1 (TLOC1))

Autre désignation: SEC62

Sujet: SEC62 Antibody: SEC62 is an integral membrane protein located in the rough endoplasmic reticulum (ER) and is part of the SEC61-SEC62-SEC63 complex that is the central component of the protein translocation apparatus of the ER membrane. It is speculated that SEC61-SEC62-SEC63 may perform post-translational protein translocation into the ER and might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. Silencing of this gene with RNAi dramatically reduced the migration and invasive potential of numerous tumor cell lines, suggesting that it may be an attractive target for therapy of various tumors.

ID gène: 7095

NCBI Accession: NP_003253

UniProt: Q99442