Strumpellin anticorps (C-Term)

N° du produit ABIN6991586

L’anticorps anti-Strumpellin Polyclonal Lapin est utilisé pour la détection de Strumpellin dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour Strumpellin anticorps (C-Term) (ABIN6991586)

Antigène: Strumpellin (WASHC5) (WASH Complex Subunit 5 (WASHC5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Strumpellin est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Strumpellin anticorps

Épitope: C-Term

Specificité: Multiple isoforms of Strumpellin are known to exist.

Purification: Strumpellin Antibody is affinity chromatography purified via peptide column.

Immunogène: Strumpellin antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human Strumpellin. The immunogen is located within the last 50 amino acids of Strumpellin.

Isotype: IgG

Information d'application

Indications d'application: Strumpellin antibody can be used for detection of Strumpellin by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Strumpellin Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: Strumpellin antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur Strumpellin

Antigène: Strumpellin (WASHC5) (WASH Complex Subunit 5 (WASHC5))

Autre désignation: Strumpellin

Sujet: Strumpellin Antibody: Strumpellin is a ubiquitously expressed, multi-transmembrane and spectrin-repeat-containing protein. It is named for Strumpell disease, a progressive upper-motor neurodegenerative disease termed hereditary spastic paraplegia (HSP). The Strumpellin gene maps to the eighth HSP locus (SPG8) on chromosome 8p24.13. Three families liked to this locus have mutations in the Strumpellin gene, rescue studies of zebrafish with decreased Strumpellin expression with Strumpellin mRNA containing these mutations showed impaired normal function of this protein. Recent studies suggest that Strumpellin may also be involved in protein aggregation diseases.

ID gène: 9897

NCBI Accession: NP_055661

UniProt: Q12768