Strumpellin anticorps (AA 1109-1159)

N° du produit ABIN7450762

Détail du produit anti-Strumpellin anticorps

Antigène: Strumpellin (WASHC5) (WASH Complex Subunit 5 (WASHC5))

Épitope: AA 1109-1159

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Strumpellin est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Fonction: Rabbit anti-SPG8/Strumpellin Antibody, Affinity Purified

Homologie: Zebrafish,Orangutan

Purification: Affinity Purified

Immunogène: Between AA 1109 and 1159

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Strumpellin

Antigène: Strumpellin (WASHC5) (WASH Complex Subunit 5 (WASHC5))

Autre désignation: SPG8/Strumpellin (WASHC5 Produits)

Synonymes: anticorps SPG8, anticorps AL022848, anticorps C76463, anticorps Kiaa0196, anticorps mKIAA0196, anticorps strumpellin, anticorps WASH complex subunit 5, anticorps WASHC5, anticorps washc5, anticorps Washc5

Sujet: Background: SPG8/Strumpellin acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization involved in regulation of the fission of tubules that serve as transport intermediates during endosome sorting (PubMed:19922875, PubMed:20498093). SPG8/Strumpellin may be involved in axonal outgrowth [taken from the Universal Protein Resource (UniProt) Q12768].

ID gène: 9897

UniProt: Q12768