LEMD3 anticorps (C-Term)

N° du produit ABIN6991613

L’anticorps anti-LEMD3 Polyclonal Lapin est utilisé pour la détection de LEMD3 dans des échantillons de Humain et Souris. Il a été validé pour WB, IF, ELISA et IHC (p).

Aperçu rapide pour LEMD3 anticorps (C-Term) (ABIN6991613)

Antigène: LEMD3 (LEM Domain Containing 3 (LEMD3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LEMD3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-LEMD3 anticorps

Épitope: C-Term

Specificité: At least three isoforms of LEMD3 are known to exist, this antibody will detect all isoforms. LEMD3 antibody is predicted to not cross-react with LEMD1 and LEMD2

Purification: LEMD3 Antibody is affinity chromatography purified via peptide column.

Immunogène: LEMD3 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human LEMD3. The immunogen is located within the last 50 amino acids of LEMD3.

Isotype: IgG

Information d'application

Indications d'application: LEMD3 antibody can be used for detection of LEMD3 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: LEMD3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: LEMD3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur LEMD3

Antigène: LEMD3 (LEM Domain Containing 3 (LEMD3))

Autre désignation: LEMD3

Sujet: LEMD3 Antibody: LEMD3 (LEM domain-containing 3) is a lem-domain containing protein, also known as MAN1, whose loss of function results in disorders characterized by osteopoikilosis, Buschke-Ollendorff syndrome, and melorheostosis. LEMD3 is an inner nuclear membrane protein that interacts with BMP and activin-TGF-beta receptor-activated Smads and antagonizes TGF-beta signaling in human cells.

ID gène: 23592

NCBI Accession: NP_055134

UniProt: Q9Y2U8