LEMD3 anticorps (AA 535-852)
Aperçu rapide pour LEMD3 anticorps (AA 535-852) (ABIN8005323)
Antigène
Voir toutes LEMD3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Épitope
- AA 535-852
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Fonction
- Anti-LEMD3 Antibody
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Réactivité croisée (Details)
- No cross reactivity with other proteins.
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Attributs du produit
- Anti-LEMD3 Antibody. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human LEMD3 recombinant protein (Position: H535-H852).
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Isotype
- IgG
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Indications d'application
- Western blot, 0.25-0.5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Date de péremption
- 12 months
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- LEMD3 (LEM Domain Containing 3 (LEMD3))
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Autre désignation
- LEMD3
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Sujet
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Background: LEM domain-containing protein 3 (LEMD3), also known as MAN1, is an integral protein in the inner nuclear membrane (INM) of the nuclear envelope. It is encoded by the LEMD3 gene[5] and was first identified after it was isolated from the serum of a patient with a collagen vascular disease. This locus encodes a LEM domain-containing protein. The encoded protein functions to antagonize transforming growth factor-beta signaling at the inner nuclear membrane. Two transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis.
Gene Full Name: LEM domain containing 3
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Poids moléculaire
- 120 kDa
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ID gène
- 23592
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UniProt
- Q9Y2U8
Antigène
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