TFEB anticorps (C-Term)

N° du produit ABIN6991678

Cet anticorps Lapin Polyclonal détecte spécifiquement TFEB dans ELISA, IF et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour TFEB anticorps (C-Term) (ABIN6991678)

Antigène: TFEB (Transcription Factor EB (TFEB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TFEB est non-conjugé

Application: ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-TFEB anticorps

Épitope: AA 390-440, C-Term

Specificité: TFEB antibody is human specific. At least three isoforms of TFEB are known to exist.

Purification: TFEB antibody is affinity chromatography purified via peptide column.

Immunogène: Rabbit polyclonal TFEB antibody was raised against a 16 amino acid peptide near the carboxy terminus of human TFEB. The immunogen is located within amino acids 390 - 440 of TFEB.

Isotype: IgG

Information d'application

Indications d'application: TFEB antibody can be used for detection of TFEB by immunohistochemistry at 2.5 μ,g/mL.

Antibody validated: Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: TFEB antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: TFEB antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur TFEB

Antigène: TFEB (Transcription Factor EB (TFEB))

Autre désignation: TFEB

Sujet: The Transcription factor EB (TFEB) is a member in the basic helix-loop-helix leucine zipper superfamily of transcription factors that is translocated in a subset of renal tumors (1,2). Recent studies have shown that lysosomal biogenesis is regulated by TFEB (3), which is in turn regulated by the mammalian target of rapamycin (mTOR) complex 1 (4). Other evidence suggests that TFEB coordinates the major steps of the autophagic pathway by driving the expression of autophagy and lysosomal genes (5).

ID gène: 7942

NCBI Accession: NP_009093

UniProt: P19484