EED anticorps (N-Term)
Aperçu rapide pour EED anticorps (N-Term) (ABIN6991742)
Antigène
Voir toutes EED AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 30-80, N-Term
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Specificité
- Four alternatively spliced transcript variants have been observed.
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Purification
- EED Antibody is affinity chromatography purified via peptide column.
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Immunogène
- EED antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human EED. The immunogen is located within amino acids 30 - 80 of EED.
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Isotype
- IgG
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Indications d'application
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EED antibody can be used for detection of EED by Western blot at 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- EED Antibody is supplied in PBS containing 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,4 °C
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Stockage commentaire
- EED antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- EED (Embryonic Ectoderm Development (EED))
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Autre désignation
- EED
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Sujet
- EED Antibody: The EED protein (WAIT-1 or WD protein associated with integrin cytoplasmic tails-1), also called embryonic ectoderm development, is a member of the superfamily of WD-40 repeat proteins and widely conserved polycomb group (PcG) family of proteins. The polycomb group (PcG) is a large and evolutionarily conserved set of genes whose products act in multimeric complexes to modify histones, which are then thought to cause stable and heritable states of transcriptional repression. EED shuttles between the nucleus and the plasma membrane and can interact with the cytoplasmic tail of integrin β,7 subunit. EED exerted an antiviral activity at the late stage of HIV-1 replication.
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Poids moléculaire
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Predicted: 49 kDa
Observed: 49 kDa -
ID gène
- 8726
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NCBI Accession
- NP_003788
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UniProt
- O75530
Antigène
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