BATF anticorps (N-Term)

N° du produit ABIN6991768

Cet anticorps Lapin Polyclonal détecte spécifiquement BATF dans ELISA, WB et IF. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour BATF anticorps (N-Term) (ABIN6991768)

Antigène: BATF (Basic Leucine Zipper ATF-like Transcription Factor (BATF))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BATF est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-BATF anticorps

Épitope: N-Term

Specificité: Multiple isoforms of BATF are known to exist. Despite its predicted molecular weight, BATF often migrates at a higher than expected molecular weight.

Purification: BATF Antibody is affinity chromatography purified via peptide column.

Immunogène: BATF antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human BATF. The immunogen is located within the first 50 amino acids of BATF.

Isotype: IgG

Information d'application

Indications d'application: BATF antibody can be used for detection of BATF by Western blot at 0.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: BATF Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: BATF antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur BATF

Antigène: BATF (Basic Leucine Zipper ATF-like Transcription Factor (BATF))

Autre désignation: BATF

Sujet: BATF Antibody: BATF is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. The leucine zipper of this protein mediates dimerization with members of the Jun family of proteins. This protein is thought to be a negative regulator of AP-1/ATF transcriptional events and blocks cellular transformation by Ras and Fos. BATF also is required for the differentiation of IL-17-producing T helper (TH17) cells, a CD4+ subset of T cells that coordinates the inflammatory response in host defense. In both T cells and B cells, BATF is required for the appropriate regulation of the class-switch recombination.

Poids moléculaire: 14 kDa

ID gène: 10538

NCBI Accession: NP_006390

UniProt: Q16520