CRB1 anticorps (AA 780-830)

N° du produit ABIN6991795

Détail du produit anti-CRB1 anticorps

Antigène: CRB1 (Crumbs Homolog 1 (CRB1))

Épitope: AA 780-830

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRB1 est non-conjugé

Application: ELISA, Western Blotting (WB)

Specificité: Alternatively spliced transcript variants have been observed. CRB1 antibody i spredicted to not cross-react with CRB2.

Purification: CRB1 Antibody is affinity chromatography purified via peptide column.

Immunogène: Rabbit polyclonal CRB1 antibody was raised against an 18 amino acid peptide near the center of human CRB1. The immunogen is located within amino acids 780 - 830 of CRB1.

Isotype: IgG

Information d'application

Indications d'application: CRB1 antibody can be used for detection of CRB1 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: CRB1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: CRB1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur CRB1

Antigène: CRB1 (Crumbs Homolog 1 (CRB1))

Autre désignation: CRB1 (CRB1 Produits)

Synonymes: anticorps CRB1, anticorps si:dkey-114d20.6, anticorps si:dkey-114d20.7, anticorps LCA8, anticorps RP12, anticorps 7530426H14Rik, anticorps A930008G09Rik, anticorps crumbs 1, cell polarity complex component, anticorps crumbs family member 1, photoreceptor morphogenesis associated, anticorps CRB1, anticorps crb1, anticorps Crb1

Sujet: CRB1 Antibody: CRB1 (Crumbs homolog 1) plays a role in photoreceptor morphogenesis in the retina. It may maintain cell polarization and adhesion. CRB1 is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. The first identified human homolog, CRB1, is expressed in retina and some parts of the brain, leaving room for another homolog to function in epithelial tissues. Mutations in this gene are associated with a severe form of retinitis pigmentosa, RP12, and with Leber congenital amaurosis.

Poids moléculaire: Predicted: 142 kDa

ID gène: 23418

NCBI Accession: NP_001180569

UniProt: P82279

Pathways: Signalisation Notch