JAKMIP1 anticorps (AA 260-310)
Aperçu rapide pour JAKMIP1 anticorps (AA 260-310) (ABIN6991799)
Antigène
Voir toutes JAKMIP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 260-310
-
Specificité
- Multiple isoforms of JAKMIP1 are known to exist. JAKMIP1 antibody is predicted to not cross-react with JAKMIP2.
-
Purification
- JAKMIP1 Antibody is affinity chromatography purified via peptide column.
-
Immunogène
- Rabbit polyclonal JAKMIP1 antibody was raised against a 16 amino acid peptide near the center of human JAKMIP1. The immunogen is located within amino acids 260 - 310 of JAKMIP1.
-
Isotype
- IgG
-
-
-
-
Indications d'application
-
JAKMIP1 antibody can be used for detection of JAKMIP1 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested. -
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- JAKMIP1 Antibody is supplied in PBS containing 0.02 % sodium azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C,4 °C
-
Stockage commentaire
- JAKMIP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
-
-
- JAKMIP1 (Janus Kinase and Microtubule Interacting Protein 1 (JAKMIP1))
-
Autre désignation
- JAKMIP1
-
Sujet
- JAKMIP1 Antibody: JAKMIP1, also known as Marlin-1, is a highly-conserved vertebrate-specific microtubule-associated protein that plays a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements. JAKMIP1 is expressed predominantly in neuronal and lymphoid cells and colocalizes with microtubules. Multiple isoforms of JAKMIP1 are known to exist: isoforms 1 and 5 are also expressed in liver, lung and skeletal muscle, while isoforms 2-4 are specifically expressed in brain and retina. JAKMIP1 participates in polarized secretion in lymphocytes and it has been suggested to be a novel effector memory gene restraining T cell-mediated cytotoxicity. Dysregulation of JAKMIP1 gene expression is associated with genetic conditions linked to autism in humans.
-
Poids moléculaire
- Predicted: 69 kDa
-
ID gène
- 152789
-
NCBI Accession
- NP_653321
-
UniProt
- Q96N16
-
Pathways
- SARS-CoV-2 Protein Interactome
Antigène
-