TPT1 anticorps (AA 80-130)

N° du produit ABIN6991810

Cet anticorps Lapin Polyclonal détecte spécifiquement TPT1 dans WB, ELISA, IF et IHC (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour TPT1 anticorps (AA 80-130) (ABIN6991810)

Antigène: TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TPT1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-TPT1 anticorps

Épitope: AA 80-130

Purification: TPT1 Antibody is affinity chromatography purified via peptide column.

Immunogène: Rabbit polyclonal TPT1 antibody was raised against a 19 amino acid peptide near the center of human TPT1. The immunogen is located within amino acids 80 - 130 of TPT1.

Isotype: IgG

Information d'application

Indications d'application: TPT1 antibody can be used for detection of TPT1 by Western blot at 0.5 - 1 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: TPT1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: TPT1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur TPT1

Antigène: TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))

Autre désignation: TPT1

Sujet: TPT1 Antibody: TPT1 (translationally controlled tumor protein 1) is a 23 kDa member of the TCTP family of calcium binding proteins. TPT1 is localized in the cytoplasm and widely expressed and serves as a transcriptional activator, calcium transporter, histamine inducer and antiapoptotic caspase 3 inhibitor. TPT1 is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. TPT1 plays a pivotal role in allergic diseases and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer's disease and Down syndrome.

Poids moléculaire: Predicted: 19 kDa

ID gène: 7178

NCBI Accession: NP_003286

UniProt: P13693

Pathways: Response to Water Deprivation, Regulation of Cell Size, Negative Regulation of intrinsic apoptotic Signaling