AGR2 anticorps (N-Term)

N° du produit ABIN6991826

L’anticorps Lapin Polyclonal anti-AGR2 a été validé pour WB, ELISA, IF et IHC (p). Il convient pour détecter AGR2 dans des échantillons de Humain et Souris.

Aperçu rapide pour AGR2 anticorps (N-Term) (ABIN6991826)

Antigène: AGR2 (Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AGR2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-AGR2 anticorps

Épitope: N-Term

Specificité: Two isoforms of AGR2 exists as a result of alternative splicing event.

Purification: AGR2 Antibody is affinity chromatography purified via peptide column.

Immunogène: Rabbit polyclonal AGR2 antibody was raised against a 17 amino acid peptide near the amino terminus of human AGR2. The immunogen is located within the first 50 amino acids of AGR2.

Isotype: IgG

Information d'application

Indications d'application: AGR2 antibody can be used for detection of AGR2 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: AGR2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: AGR2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur AGR2

Antigène: AGR2 (Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2))

Autre désignation: AGR2

Sujet: AGR2 Antibody: AGR2 (anterior gradient protein 2) and AGR3 are members of the anterior gradient homolog family. They are secreted cytoplasmic proteins which are involved in metastasis induction and p53 tumour supressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumours. AGR2 is ubiquitously expressed with upregulated expression in prostate cancer, breast cancer, lung cancer, renal carcinomas and endometrial carcinomas. AGR2 expression is positively correlated with that of the estrogen receptor (ER) and is negatively correlated with that of the epidermal growth factor receptor (EGFR).

Poids moléculaire: 19 kDa

ID gène: 10551

NCBI Accession: NP_006399

UniProt: O95994