TRIM24 anticorps (AA 530-580)

N° du produit ABIN6991871

L’anticorps anti-TRIM24 Polyclonal Lapin est utilisé pour la détection de TRIM24 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IF et ICC.

Aperçu rapide pour TRIM24 anticorps (AA 530-580) (ABIN6991871)

Antigène: TRIM24 (Tripartite Motif Containing 24 (TRIM24))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIM24 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-TRIM24 anticorps

Épitope: AA 530-580

Specificité: At least two isoforms of TRIM24 are known to exist.

Purification: TRIM24 Antibody is affinity chromatography purified via peptide column.

Immunogène: TRIM24 antibody was raised against a 19 amino acid peptide near the center of human TRIM24. The immunogen is located within amino acids 530 - 580 of TRIM24.

Isotype: IgG

Information d'application

Indications d'application: TRIM24 antibody can be used for detection of TRIM24 by Western blot at 0.5 - 1 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: TRIM24 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: TRIM24 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur TRIM24

Antigène: TRIM24 (Tripartite Motif Containing 24 (TRIM24))

Autre désignation: TRIM24

Sujet: TRIM24 Antibody: TRIM24 (TIF1), a member of the tripartite motif (TRIM) family, plays a role in the regulation of cell proliferation and apoptosis. TRIM24 localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The TRIM motif includes three zinc-binding domains (RING, B-box type 1 and B-box type 2) and a coiled-coil region. TIF1 mediates transcriptional events by interactions with the AF2 region of several nuclear receptors, such as the estrogen, retinoic acid and vitamin D3 receptors. Defects in TRIM24 are a cause of thyroid papillary carcinoma (TPC).

Poids moléculaire: Predicted: 112, 116

Observed: 108, 1 of 2 isoforms kDa

ID gène: 8805

NCBI Accession: NP_056989

UniProt: O15164