GOLGA5 anticorps (C-Term)

N° du produit ABIN6991873

Cet anticorps Lapin Polyclonal détecte spécifiquement GOLGA5 dans WB, ELISA, IF et IHC (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour GOLGA5 anticorps (C-Term) (ABIN6991873)

Antigène: GOLGA5 (Golgin A5 (GOLGA5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GOLGA5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-GOLGA5 anticorps

Épitope: AA 540-590, C-Term

Specificité: GOLGA5 antibody is human, mouse and rat reactive. Two isoforms of GOLGA5 exist due to alternative splicing events.

Purification: GOLGA5 Antibody is affinity chromatography purified via peptide column.

Immunogène: GOLGA5 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human GOLGA5. The immunogen is located within amino acids 540 - 590 of GOLGA5.

Isotype: IgG

Information d'application

Indications d'application: GOLGA5 antibody can be used for detection of GOLGA5 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: GOLGA5 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: GOLGA5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur GOLGA5

Antigène: GOLGA5 (Golgin A5 (GOLGA5))

Autre désignation: GOLGA5

Sujet: GOLGA5 Antibody: GOLGA5 (Golgi autoantigen, subfamily A, member 5), also known as GOLGA84, RFG5 (RET-fused gene 5 protein) or GOLIM5, is a ubiquitously expressed single-pass type II coiled-coil membrane protein that is involved in maintaining Golgi structure (1). It is localized to the Golgi apparatus and predominantly found on membranes at the cis side of the Golgi stack (1,2). As a mitotic phosphoprotein, GOLGA5 binds to active Rab 1 and associates with CASP (an isoform of CDP) in a golgin-tethering complex that is believed to play a role in intra-Golgi retrograde transport (3,4). Defects in GOLGA5 are a cause of thyroid papillary carcinoma (TPC) (5).

Poids moléculaire: Predicted: 64, 80 kDa

Observed: 65, 78 kDa

ID gène: 9950

NCBI Accession: NP_005104

UniProt: Q8TBA6