Lipin 1 anticorps (C-Term)

N° du produit ABIN6991876

Cet anticorps Lapin Polyclonal détecte spécifiquement Lipin 1 dans WB, ELISA, IHC (p) et IF. Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour Lipin 1 anticorps (C-Term) (ABIN6991876)

Antigène: Lipin 1 (LPIN1)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Lipin 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-Lipin 1 anticorps

Épitope: C-Term

Specificité: LPIN1 antibody is human and mouse reactive. At least four isoforms of LPIN1 are known to exist.

Purification: LPIN1 Antibody is affinity chromatography purified via peptide column.

Immunogène: LPIN1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human LPIN1. The immunogen is located within the last 50 amino acids of LPIN1.

Isotype: IgG

Information d'application

Indications d'application: LPIN1 antibody can be used for detection of LPIN1 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: LPIN Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: LPIN antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur Lipin 1

Antigène: Lipin 1 (LPIN1)

Autre désignation: LPIN1

Sujet: LPIN1 Antibody: LPIN1, also known as PAP1, is a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol (reviewed in 1). LPIN1 is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism (1,2). Mutations in LPIN1 are associated with metabolic diseases such as type 2 diabetes and recurrent acute myoglobinuria (3,4) and it is also a candidate for several human lipodystrophy syndromes (5).

Poids moléculaire: Predicted: 107 kDa

Observed: 125 kDa

ID gène: 23175

NCBI Accession: NP_001248357

UniProt: Q14693

Pathways: Monocarboxylic Acid Catabolic Process