Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
Specificité
NCBP1 antibody is human, mouse and rat reactive. At least two isoforms of NCBP1 are known to exist, this antibody will detect both isoforms of NCBP1.
Purification
NCBP1 Antibody is affinity chromatography purified via peptide column.
Immunogène
NCBP1 antibody was raised against a 17 amino acid peptide near the center of human NCBP1. The immunogen is located within amino acids 420 - 470 of NCBP1.
anticorps CBP80, anticorps CG7035, anticorps Dmel\\CG7035, anticorps EG:84H4.3, anticorps ncbp, anticorps sto1, anticorps cbp80, anticorps AU014645, anticorps AW538051, anticorps NCBP, anticorps Sto1, anticorps ncbp1, anticorps ABA HYPERSENSITIVE 1, anticorps ATCBP80, anticorps CAP-BINDING PROTEIN 80, anticorps ENS, anticorps ENSALADA, anticorps NUCLEAR CAP-BINDING PROTEIN CBP80, anticorps T10F5.8, anticorps T10F5_8, anticorps cap binding protein 80, anticorps nuclear cap binding protein subunit 1, anticorps nuclear cap binding protein subunit 1 S homeolog, anticorps nuclear cap binding protein subunit 1, 80kDa, anticorps nuclear cap binding protein subunit 1 L homeolog, anticorps ARM repeat superfamily protein, anticorps Nuclear cap-binding protein subunit 1-A, anticorps Nuclear cap-binding protein subunit 1, anticorps Cbp80, anticorps ncbp1, anticorps ncbp1.S, anticorps NCBP1, anticorps Ncbp1, anticorps ncbp1.L, anticorps ABH1, anticorps nbp1a, anticorps ncbp-1
Sujet
NCBP1 Antibody: NCBP1, also known as CBP80, is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. NCBP1 promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay (1,2). Recent evidence has shown that cellular-cap-binding proteins such as NCBP1 associate with influenza virus mRNAs, suggesting that these viral mRNAs may follow the normal cellular pathways for splicing, nuclear export, and translation (3).