MAP1LC3A anticorps (N-Term)

N° du produit ABIN6991931

L’anticorps Lapin Polyclonal anti-MAP1LC3A a été validé pour WB, ELISA, IF et IHC (p). Il convient pour détecter MAP1LC3A dans des échantillons de Humain.

Aperçu rapide pour MAP1LC3A anticorps (N-Term) (ABIN6991931)

Antigène: MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP1LC3A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-MAP1LC3A anticorps

Épitope: N-Term

Specificité: MAP1LC3A antibody is human specific. At least two isoforms of MAP1LC3A are known to exist. MAP1LC3A antibody is predicted to not cross-react with MAP1LC3B or MAP1LC3C.

Purification: MAP1LC3A antibody is affinity chromatography purified via peptide column.

Immunogène: MAP1LC3A antibody was raised against a 10 amino acid peptide near the amino terminus of human MAP1LC3A. The immunogen is located within the first 50 amino acids of MAP1LC3A.

Isotype: IgG

Information d'application

Indications d'application: MAP1LC3A antibody can be used for detection of MAP1LC3A by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: MAP1LC3A antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: MAP1LC3A antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur MAP1LC3A

Antigène: MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

Autre désignation: MAP1LC3A

Sujet: Microtubule-associated proteins (MAPs) regulate microtubule stability and play critical roles in neuronal development and plasticity (1). MAP1LC3A belongs to the MAP1 LC3 family of proteins that form mature complexes with MAP1A and MAP1B which are thought to be important in the formation and development of axons and dendrites (2). MAP1LC3A is one of three isoforms of MAP1LC3, the mammalian homolog of yeast ATG8, an essential autophagy protein. These isoforms exhibit distinct expression patterns and MAP1LC3A, like MAP1LC3A but not MAP1LC3B, is post-translationally modified, suggesting the three isoforms may have different physiological functions (3).

Poids moléculaire: Predicted: 14 kDa

Observed: 17 kDa

ID gène: 84557

NCBI Accession: NP_852610

UniProt: Q9H492

Pathways: Autophagy