ULK4 anticorps (C-Term)

N° du produit ABIN6991935

Cet anticorps anti-ULK4 est un anticorps Lapin Polyclonal détectant ULK4 dans WB, ELISA, IF et IHC (p). Adapté pour Humain et Souris.

Aperçu rapide pour ULK4 anticorps (C-Term) (ABIN6991935)

Antigène: ULK4 (ULK24) (Unc-51-Like Kinase 4 (ULK24))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ULK4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-ULK4 anticorps

Épitope: AA 1120-1170, C-Term

Specificité: ULK4 antibody is human and mouse reactive. Multiple isoforms of ULK4 are known to exist.

Purification: ULK4 antibody is affinity chromatography purified via peptide column.

Immunogène: ULK4 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human ULK4. The immunogen is located within amino acids 1120 - 1170 of ULK4.

Isotype: IgG

Information d'application

Indications d'application: ULK4 antibody can be used for detection of ULK4 by Western blot at 0.5 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: ULK4 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: ULK4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur ULK4

Antigène: ULK4 (ULK24) (Unc-51-Like Kinase 4 (ULK24))

Autre désignation: ULK4

Sujet: ULK4 belongs to the Ser/Thr protein kinase superfamily and plays a role in the ATP-dependent phosphorylation of target proteins (1). Knockout of ULK genes results in a severe defect in the autophagy pathway (2). ULK4, like the other Unc-51-like kinases such as ULK1, ULK2 and ULK3, is highly conserved among eukaryotes (3). ULK4 has been implicated as a gene involved in the development of hydrocephalus (3). This neurologic disorder is being used in animal models to elucidate factors responsible for the excessive accumulation of cerebrospinal fluid in hydrocephalic humans (4).

Poids moléculaire: Predicted: 140 kDa

Observed: 165 kDa

ID gène: 54986

NCBI Accession: NP_060356

UniProt: Q96C45