CXCL12 anticorps

N° du produit ABIN6991936

Cet anticorps Lapin Polyclonal détecte spécifiquement CXCL12 dans WB, ELISA et ICC. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour CXCL12 anticorps (ABIN6991936)

Antigène: CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CXCL12 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Détail du produit anti-CXCL12 anticorps

Specificité: CXCL12 antibody is human and mouse reactive. Multiple isoforms of CXCL12 are known to exist.

Purification: CXCL12 antibody is affinity chromatography purified via peptide column.

Immunogène: CXCL12 antibody was raised against a 16 amino acid peptide near the center of human CXCL12 . The immunogen is located within the last 50 amino acids of CXCL12.

Isotype: IgG

Information d'application

Indications d'application: CXCL12 antibody can be used for detection of CXCL12 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunocytochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: CXCL12 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: CXCL12 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur CXCL12

Antigène: CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))

Autre désignation: CXCL12

Sujet: The CXCL12 protein, also known as SDF1, is a stromal cell-derived alpha chemokine member of the intercrine family. CXCL12 functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4 (CXCR4) and CXCR7, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis (reviewed in 1). Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections (2).

Poids moléculaire: Predicted: 15 kDa

Observed: 18 kDa

ID gène: 6387

NCBI Accession: NP_001171605

UniProt: P48061

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events, Negative Regulation of intrinsic apoptotic Signaling