AQP2 anticorps (C-Term)

N° du produit ABIN6991948

Détail du produit anti-AQP2 anticorps

Antigène: AQP2 (Aquaporin 2 (Collecting Duct) (AQP2))

Épitope: C-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AQP2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: AQP2 antibody is human, mouse and rat reactive. This antibody is predicted to not cross-react with other members of the aquaporin protein family.

Purification: AQP2 antibody is affinity chromatography purified via peptide column.

Immunogène: AQP2 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human AQP2. The immunogen is located within the last 50 amino acids of AQP2.

Isotype: IgG

Information d'application

Indications d'application: AQP2 antibody can be used for detection of AQP2 by Western blot at 1 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: AQP2 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: AQP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur AQP2

Antigène: AQP2 (Aquaporin 2 (Collecting Duct) (AQP2))

Autre désignation: AQP2 (AQP2 Produits)

Synonymes: anticorps AQP-CD, anticorps WCH-CD, anticorps cph, anticorps jpk, anticorps AQP-2, anticorps aquaporin-2, anticorps aquaporin 2, anticorps aquaporin 2 (collecting duct), anticorps Aqp2, anticorps AQP2

Sujet: Aquaporins are membrane proteins that serve in the transfer of water and small solutes across cellular membranes. One such aquaporin, aquaporin-2 (AQP2) is located in the kidney collecting tubule and plays a critical role in water reabsorbtion (1). AQP2 is mainly localized in intracellular vesicles but upon stimulation with anti-diuretic hormone (ADH), AQP2 is translocated to the apical plasma membrane by exocytic fusion of AQP2-bearing vesicles (2). Mutations in this gene have been linked to autosomal dominant and recessive forms of nephrogenic diabetes insipidus (3).

Poids moléculaire: Predicted: 30 kDa

Observed: 28 kDa

ID gène: 359

NCBI Accession: NP_000477

UniProt: P41181

Pathways: Response to Water Deprivation