GLIPR1 anticorps (AA 60-110)

N° du produit ABIN6991949

L’anticorps anti-GLIPR1 Polyclonal Lapin est utilisé pour la détection de GLIPR1 dans des échantillons de Humain et Souris. Il a été validé pour ELISA, WB et IF.

Aperçu rapide pour GLIPR1 anticorps (AA 60-110) (ABIN6991949)

Antigène: GLIPR1 (GLI Pathogenesis-Related 1 (GLIPR1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLIPR1 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-GLIPR1 anticorps

Épitope: AA 60-110

Specificité: GLIPR1 antibody is human and mouse reactive. At least two isoforms of GLIPR1 are known to exist, this antibody will detect both isoforms. This antibody is predicted to not cross-react with other GLIPR or GLIPR-like proteins.

Purification: GLIPR1 antibody is affinity chromatography purified via peptide column.

Immunogène: GLIPR1 antibody was raised against an 18 amino acid peptide near the center of human GLIPR1. The immunogen is located within amino acids 60 - 110 of GLIPR1.

Isotype: IgG

Information d'application

Indications d'application: GLIPR1 antibody can be used for detection of GLIPR1 by Western blot at 1 - 2 μ,g/mL. For Immunoflorescence start at 5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: GLIPR1 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: GLIPR1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur GLIPR1

Antigène: GLIPR1 (GLI Pathogenesis-Related 1 (GLIPR1))

Autre désignation: GLIPR1

Sujet: The glioma pathogensis-related protein 1 (GLIPR1) is similar to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family (1). GLIPR1 is a tumor suppressor whose expression is regulated by p53, its increased expression is associated with myelomocytic differentiation in macrophages, whereas decreased expression of this gene through gene methylation is associated with prostate cancer (2). The GLIPR1 gene is part of a p53 target gene cluster that includes GLIPR1L1 and GLIPR1L2, two highly homologous proteins whose expression patterns vary (3).

Poids moléculaire: Predicted: 29 kDa

Observed: 29 kDa

ID gène: 11010

NCBI Accession: NP_006842

UniProt: P48060

Pathways: Regulation of Lipid Metabolism by PPARalpha