CCR7 anticorps (AA 180-230)

N° du produit ABIN6991956

Cet anticorps anti-CCR7 est un anticorps Lapin Polyclonal détectant CCR7 dans WB, ELISA, IF et IHC (p). Adapté pour Humain.

Aperçu rapide pour CCR7 anticorps (AA 180-230) (ABIN6991956)

Antigène: CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCR7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CCR7 anticorps

Épitope: AA 180-230

Specificité: CCR7 antibody is human specific. CCR7 antibody is predicted to not cross-react with other CCR proteins.

Purification: CCR7 antibody is affinity chromatography purified via peptide column.

Immunogène: CCR7 antibody was raised against a 15 amino acid peptide near the center of human CCR7. The immunogen is located within amino acids 180 - 230 of CCR7.

Isotype: IgG

Information d'application

Indications d'application: CCR7 antibody can be used for detection of CCR7 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: CCR7 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: CCR7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur CCR7

Antigène: CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

Autre désignation: CCR7

Sujet: The CCR7 protein is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation (1,2). The chemokine (C-C motif) ligand 19 (CCL19) has been reported to be a specific ligand of this receptor (3).

Poids moléculaire: Predicted: 42 kDa

Observed: 42 kDa

ID gène: 1236

NCBI Accession: NP_001829

UniProt: P32248

Pathways: Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process