NINJ1 anticorps (C-Term)

N° du produit ABIN6992062

Cet anticorps Lapin Polyclonal détecte spécifiquement NINJ1 dans WB, ELISA, IF et IHC (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour NINJ1 anticorps (C-Term) (ABIN6992062)

Antigène: NINJ1 (Ninjurin 1 (NINJ1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NINJ1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-NINJ1 anticorps

Épitope: C-Term

Specificité: NINJ1 antibody is human, mouse and rat reactive.

Purification: NINJ1 antibody is affinity chromatography purified via peptide column.

Immunogène: NINJ1 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human NINJ1. The immunogen is located within the last 50 amino acids of NINJ1.

Isotype: IgG

Information d'application

Indications d'application: NINJ1 antibody can be used for detection of NINJ1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: NINJ1 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: NINJ1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur NINJ1

Antigène: NINJ1 (Ninjurin 1 (NINJ1))

Autre désignation: NINJ1

Sujet: Ninjurin-1 (NINJ1) is a homophilic adhesion molecule that is strongly induced in dorsal root ganglion (DRG) and Schwann cells following nerve injury and promotes neurite outgrowth of DRG neurons (1,2), suggesting that NINJ1 may play a role in nerve regeneration. NINJ1 is transcriptionally regulated by p53 and is induced by DNA damage in a p53-dependent manner. A deficiency of NINJ1 increases p53 expression, suppresses cell proliferation, but enhances apoptosis and premature senescence in a p53-dependent manner as well as radiation-induced cell mortality (3).

Poids moléculaire: Predicted: 17 kDa

Observed: 16 kDa

ID gène: 4814

NCBI Accession: NP_004139

UniProt: Q92982