GJB2 anticorps (AA 80-130)

N° du produit ABIN6992084

L’anticorps Lapin Polyclonal anti-GJB2 a été validé pour WB et ELISA. Il convient pour détecter GJB2 dans des échantillons de Humain.

Aperçu rapide pour GJB2 anticorps (AA 80-130) (ABIN6992084)

Antigène: GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GJB2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-GJB2 anticorps

Épitope: AA 80-130

Specificité: GJB2 antibody is human specific.

Purification: GJB2 antibody is affinity chromatography purified via peptide column.

Immunogène: GJB2 antibody was raised against a 16 amino acid peptide near the center of human GJB2. The immunogen is located within amino acids 80 - 130 of GJB2.

Isotype: IgG

Information d'application

Indications d'application: GJB2 antibody can be used for detection of GJB2 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: GJB2 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: GJB2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur GJB2

Antigène: GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))

Autre désignation: GJB2

Sujet: The Gap junction beta-2 protein (GJB2), also known as Connexin 26, is member of the gap junction protein family which form structures that were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells (1). Mutations in the GJB2 gene are thought to be responsible for as much as 35-45 % of congenital sensorineural hearing loss in some populations (2). Other mutations in this gene have also been linked to a wide array of skin diseases (3).

Poids moléculaire: Predicted: 25 kDa

Observed: 26 kDa

ID gène: 2706

NCBI Accession: NP_003995

UniProt: P29033

Pathways: Sensory Perception of Sound, Cell-Cell Junction Organization