MEK1/2 anticorps (AA 240-290)

N° du produit ABIN6992146

Cet anticorps Lapin Polyclonal détecte spécifiquement MEK1/2 dans WB, ELISA, IF et IHC (p). Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour MEK1/2 anticorps (AA 240-290) (ABIN6992146)

Antigène: MEK1/2 (MAP2K1/2) (Mitogen-Activated Protein Kinase Kinase 1/2 (MAP2K1/2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MEK1/2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-MEK1/2 anticorps

Épitope: AA 240-290

Specificité: MEK1/2 antibody is human, mouse, and rat reactive. This antibody detects both MEK1 and MEK2.

Purification: MEK1/2 antibody is affinity chromatography purified via peptide column.

Immunogène: MEK1/2 antibody was raised against a 15 amino acid peptide near the center of human MEK1. The immunogen is located within amino acids 240 - 290 of MEK1/2.

Isotype: IgG

Information d'application

Indications d'application: MEK1/2 antibody can be used for detection of MEK1/2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: MEK1/2 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: MEK1/2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur MEK1/2

Antigène: MEK1/2 (MAP2K1/2) (Mitogen-Activated Protein Kinase Kinase 1/2 (MAP2K1/2))

Autre désignation: MEK1/2

Sujet: The mitogen-activated protein kinase kinase 1 (MAP2K1, also known as MEK1) and the highly homologous MEK2 are members of the dual specificity protein kinase family (1). MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals (2). MEK1 lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, MEK1 is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development (2).

Poids moléculaire: Predicted: 43 kDa

Observed: 44 kDa

ID gène: 5604

NCBI Accession: NP_002746

UniProt: Q0VD16