Hexokinase 1 anticorps (C-Term)

N° du produit ABIN6992150

L’anticorps Lapin Polyclonal anti-Hexokinase 1 a été validé pour WB, ELISA, IF et IHC (p). Il convient pour détecter Hexokinase 1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Hexokinase 1 anticorps (C-Term) (ABIN6992150)

Antigène: Hexokinase 1 (HK1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Hexokinase 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Hexokinase 1 anticorps

Épitope: AA 830-880, C-Term

Specificité: Hexokinase 1 antibody is human, mouse and rat reactive. Multiple isoforms of Hexokinase 1 are known to exist.

Purification: Hexokinase 1 antibody is affinity chromatography purified via peptide column.

Immunogène: Hexokinase 1 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human Hexokinase 1. The immunogen is located within amino acids 830 - 880 of Hexokinase 1.

Isotype: IgG

Information d'application

Indications d'application: Hexokinase 1 antibody can be used for detection of Hexokinase 1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Hexokinase 1 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: Hexokinase 1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur Hexokinase 1

Antigène: Hexokinase 1 (HK1)

Autre désignation: Hexokinase 1

Sujet: There are four major glucose-phosphorylating isoenzymes, designated Hexokinase 1 I, II, III, and IV (1). Hexokinase 1 activity is involved in the first step in several metabolic pathways including phosphorylation of glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway (1,2). Hexokinase 1 2 is the predominant Hexokinase 1 isozyme expressed in insulin-responsive tissues such as skeletal muscle and its expression is insulin-responsive (3). It is involved in the increased rate of glycolysis seen in rapidly growing cancer cells (4).

Poids moléculaire: Predicted: 101 kDa

Observed: 103 kDa

ID gène: 3098

NCBI Accession: NP_000179

UniProt: P19367

Pathways: Carbohydrate Homeostasis, L'effet Warburg