Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificité
VTI1a antibody is human, mouse and rat reactive. At least two isoforms of VTI1a are known to exist, this antibody will detect both isoforms. VTI1a antibody is predicted to not cross-react with VTI1b.
Purification
VTI1a antibody is affinity chromatography purified via peptide column.
Immunogène
VTI1a antibody was raised against a 19 amino acid peptide near the center of human VTI1a. The immunogen is located within amino acids 50 - 100 of VTI1a.
VTI1A
Reactivité: Humain
ELISA
Hôte: Lapin
Polyclonal
Biotin
Indications d'application
VTI1a antibody can be used for detection of VTI1a by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
VTI1a antibody is supplied in PBS containing 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C,4 °C
Stockage commentaire
VTI1a antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Antigène
VTI1A
(Vesicle Transport through Interaction with t-SNAREs 1A (VTI1A))
anticorps zgc:109895, anticorps mvti1, anticorps vti1-rp2, anticorps DDBDRAFT_0219803, anticorps DDBDRAFT_0231536, anticorps DDB_0219803, anticorps DDB_0231536, anticorps MMDS3, anticorps MVti1, anticorps VTI1RP2, anticorps Vti1-rp2, anticorps 1110014F16Rik, anticorps 1110018K19Rik, anticorps 4921537J05Rik, anticorps MVti1a, anticorps Vti1, anticorps vesicle transport through interaction with t-SNAREs 1A L homeolog, anticorps vesicle transport through interaction with t-SNAREs 1A, anticorps v-SNARE family protein, anticorps vti1a.L, anticorps vti1a, anticorps VTI1A, anticorps vti1A, anticorps Vti1a
Sujet
Vesicle transport through interaction with t-SNAREs homolog 1 (VTI1a and VTI1b) are involved in vesicular transport from the late endosomes to the trans-Golgi network (1). They are both localized in the trans-Golgi network, with VTI1a also found in the Golgi apparatus and VTI1b in endosomes (2,3). VTI1a mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane and promotes fusion of the lipid bilayers (4). VTI1a may be concerned with increased secretion of cytokines associated with cellular senescence (5).