GAS6 anticorps (N-Term)

N° du produit ABIN6992169

Cet anticorps anti-GAS6 est un anticorps Lapin Polyclonal détectant GAS6 dans WB, ELISA et IHC (p). Adapté pour Humain, Souris et Rat.

Aperçu rapide pour GAS6 anticorps (N-Term) (ABIN6992169)

Antigène: GAS6 (Growth Arrest-Specific 6 (GAS6))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GAS6 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-GAS6 anticorps

Épitope: AA 60-110, N-Term

Specificité: GAS6 antibody is human, mouse and rat reactive. At least four isoforms of GAS6 are known to exist, this antibody will only detect the longest isoform.

Purification: GAS6 Antibody is affinity chromatography purified via peptide column.

Immunogène: GAS6 antibody was raised against a 19 amino acid peptide from near the amino terminus of human GAS6. The immunogen is located within amino acids 60 - 110 of GAS6.

Isotype: IgG

Information d'application

Indications d'application: GAS6 antibody can be used for the detection of GAS6 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: GAS6 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: GAS6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur GAS6

Antigène: GAS6 (Growth Arrest-Specific 6 (GAS6))

Autre désignation: GAS6

Sujet: The growth arrest-specific 6 (GAS6) protein is a gamma-carboxyglutamic acid (Gla)-containing protein and a member of a family of plasma vitamin K-dependent proteins. GAS6 is involved in vascular homeostasis, cell proliferation, apoptosis, leukocyte migration, and platelet aggregation (1,2). GAS6 is the ligand for the type I transmembrane receptor tyrosine kinase receptors Tyro3, Axl, and Mer (3). This gene is frequently overexpressed in many cancers and has been implicated as an adverse prognostic marker (4). Elevated protein levels are additionally associated with a variety of disease states, including venous thromboembolic disease, systemic lupus erythematosus, chronic renal failure, and preeclampsia (2).

Poids moléculaire: Predicted: 75 kDa

Observed: 75 kDa

ID gène: 2621

NCBI Accession: NP_000811

UniProt: Q14393

Pathways: Signalisation RTK, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response